Tiago Costa-Coelho, MSc
PhD Student
Email:
tcoelho@medicina.ulisboa.pt
Research Keywords:
BDNF/TrkB-FL, Alzheimer’s disease, Extracellular vesicles, paracrine signaling, proteasome, neuropharmacology
ORCID: 0000-0003-3097-6728
Proficiency in extracellular vesicle isolation and characterization from cell secretome and human samples, in vitro methodologies (neuroblastoma and neuroglioma cell lines, primary neuronal, bacteria and yeast cultures, plasmid and viral transduction, western-blot, co-immunoprecipitation, immunofluorescence and calcium imaging), in vivo techniques (rodent handling and welfare, behavioural tests, drug administration) and ex vivo procedures (brain isolation and dissection, cerebrospinal fluid and blood collection and electrophysiological recordings).
Tiago focuses on assessing the potential paracrine toxicity and clearance systems of a dysfunctional BDNF/TrkB signaling in Alzheimer’s disease.
Research
Skills
Education
January 2023 - January 2026
CAML PhD Program: Biomedical Sciences with specialization in Neurosciences
(Faculty of Medicine, University of Lisbon)
September 2018 - June 2021
September 2015 - June 2018
Master in Biochemistry for Health
(NOVA Medical School, University NOVA Lisbon)
Bachelor in Biochemistry
(NOVA School of Sciences and Technology, University NOVA Lisbon)